During the 1992 Presidential campaign, Republican Vice-President Dan Quayle got in a battle with television character Murphy Brown, portrayed by Candice Bergen. The previous season, the Murphy Brown character had borne a child out of wedlock. Noted spelling champion* Dan Quayle criticized this, saying it ignored the importance of fathers, and encouraged women to be single mothers.
Not only was the fight idiotic, Quayle lost, starting a grand right-wing tradition of getting into fights with fictional characters and losing. (see "Jerry Fallwell vs. The Teletubbies").
Murphy got the last laugh: at the end of an episode of Murphy Brown, a truckload of potatoes was dropped dumped at the gate of the White House.
Murphy Brown, by a knock-out
*In 1992, Quayle had infamously "corrected" a child in a Trenton, New Jersey spelling bee-- the child had correctly spelled "potato," but Mr. Quayle insisted that the correct spelling was "potatoe." The student was correct.